Data Availability
Participant data from the UK Biobank cohort was obtained through UK Biobank Access Application number 44584. The UK Biobank has approval from the North West Multi-center Research Ethics Committee (REC reference: 11/NW/0382). All methods were performed in accordance with the relevant guidelines and regulations, and informed consent was obtained from all participants. Researchers may apply to use the UK Biobank data resource by submitting a health-related research proposal that is in the public interest. More information may be found on the UK Biobank researchers and resource catalogue pages (www.ukbiobank.ac.uk).





